Neuron Morphology data in .swc format from Patch-seq experiments in mouse cortex, Cell ID 820754704

Mouse cortical neurons display diverse morphology, physiology and gene expression profiles. We use a method called Patch-seq, where these three data modalities are assayed simultaneously from the same neuron, to understand how the genetic profile of mouse cortical neuron types corresponds to their morphological and electrophysiological phenotypes. This collection may contain image stacks (TIFF), reconstruction files in image space (.swc, µm), a transformed file (.swc, µm) oriented so that the y axis extends vertically towards the pia surface, and a marker file (.marker, µm) indicating nodes where dendrites were truncated (10), reconstruction was not continued (20), or surface of tissue was closest to soma (30).

小鼠皮层神经元具有丰富多样的形态、生理特性与基因表达谱。我们采用名为Patch-seq的技术，可从同一神经元中同时获取上述三类数据模态的检测数据，以此探究小鼠皮层神经元类型的基因表达谱与其形态学及电生理学表型之间的对应关系。本数据集集合包含以下类型文件：图像栈（TIFF）、图像空间重建文件（.swc，单位：微米）、经坐标转换的重建文件（.swc，单位：微米，其Y轴垂直指向软脑膜表面），以及标记文件（.marker，单位：微米），该标记文件用于标注三类节点：树突被截断的节点（标记值10）、重建终止的节点（标记值20），以及组织表面距胞体最近的节点（标记值30）。