Guidance Document on the Recognition, Assessment and Use of Clinical Signs as Human Endpoints for Experimental Animals Used in Safety Evaluation

Organisation for Economic Co-operation and Development2026-04-11 收录

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The purpose of this Guidance Document is to apply the principles of the Three Rs to the use of animals in regulatory toxicity tests.

本指导文件旨在将3R原则（Three Rs）应用于监管毒理学试验中的动物使用场景。