Long-Term Outcomes of Pterygium Extended Removal Combined with Conjunctival Autograft and Amniotic Membrane Transplantation

To observe the Long-term results of pterygium extended removal combined conjunctival autograft and amniotic membrane transplantation This is a prospective study of 666 eyes (606 patients, 332 right eyes and 336 left eyes). All patients underwent pterygium extended removal combined conjunctival autograft and amniotic membrane transplantation in a same hospital. The primary outcome measures included the cosmetic appearances and recurrence rate; the secondary outcome measures were some serious complications, like Keratitis, conjunctival cyst and conjunctival granuloma. 606 patients (82.34% of surviving) were able to be followed up. The mean follow-up period was 29.96 ± 13.34 months. Recurrence was noted in 7 eyes (1.05%), and there were no serious complications. 89.04% of eyes were graded as having excellent cosmetic appearance. The long-term recurrence rate of pterygium extended removal combined conjunctival autograft and amniotic membrane Graft is very low, and the long-term cosmetic appearance is excellent. And also, there were no other serious complications.

本研究旨在探讨翼状胬肉延长切除术联合结膜自体移植及羊膜移植的远期疗效。本研究为前瞻性研究，共纳入666只患眼（606例患者，其中右眼332只、左眼336只），所有患者均于同一家医院接受上述手术治疗。本研究的主要结局指标包括患眼外观美观度与复发率，次要结局指标包括角膜炎、结膜囊肿、结膜肉芽肿等严重并发症。606例患者中82.34%完成随访，平均随访时长为29.96±13.34个月。随访期间共7只患眼（占比1.05%）出现复发，未发生严重并发症；89.04%的患眼被评定为外观美观效果优良。结果表明，翼状胬肉延长切除术联合结膜自体移植及羊膜移植的远期复发率极低，患眼远期外观美观效果优良，且未出现其他严重并发症。