QTLs linked to biomechanics and DXA phenotypes in male and female F2 rats. Suggestive QTLs are reported if overlapping a significant QTL.
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QTL size defined as the region covered by a 1-LOD reduction for any of the bone traits.aGenome-wide suggestive QTL (LOD≥2.3).bGenome-wide significant QTL (LOD≥3.8).cSuggestive cross-specific QTLs (ΔLODcross≥2.4) validated by likelihood ratio (LR) tests for QTL-by-cross interaction (pdSignificant cross-specific QTLs (ΔLODcross≥3.9) validated by likelihood ratio (LR) tests for QTL-by-cross interaction (p
数量性状位点(Quantitative Trait Locus, QTL)区间定义为针对任意骨骼性状,似然比对数(Logarithm of Odds, LOD)值降低1个单位所覆盖的基因组区域。a:全基因组提示性QTL(LOD≥2.3);b:全基因组显著性QTL(LOD≥3.8);c:提示性杂交组合特异性QTL(ΔLODcross≥2.4),经QTL与杂交组合互作的似然比(Likelihood Ratio, LR)检验验证;d:显著性杂交组合特异性QTL(ΔLODcross≥3.9),经QTL与杂交组合互作的似然比(LR)检验验证(原文末尾p值相关信息不完整)
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2015-12-02



