Mature intracranial teratoma with meningocele in a lamb

ABSTRACT: This study described the pathological aspects of a mature intracranial teratoma with meningocele in a one-day-old lamb. The diagnosis of mature teratoma was based on microscopic features, where well-differentiated tissues representative of the three germ layers were observed. The tumor consisted of respiratory, gastrointestinal and urinary epithelium as components of the endoderm; muscle and bone tissues as components of the mesoderm; and keratinized stratified squamous epithelium and adnexa as components of the ectoderm. To the best of our knowledge, this is the first report of intracranial teratoma with meningocele in animals.

摘要：本研究报道了1日龄羔羊伴脑膜膨出的成熟颅内畸胎瘤的病理学特征。成熟畸胎瘤的诊断基于镜下特征：可见代表三个胚层的高分化组织。该肿瘤包含内胚层来源的呼吸上皮、胃肠道上皮与尿路上皮；中胚层来源的肌肉与骨组织；以及外胚层来源的角化复层鳞状上皮及其附属结构。据我们所知，本研究为动物颅内畸胎瘤伴脑膜膨出的首次报道。