human gut metagenome Metagenomic assembly. human gut metagenome

Using 16S ribosomal DNA sequencing, we determined both the metagenomic communities and the microbe-derived EVs profile in feces of healthy subjects and patients with diarrhea, morbid obesity and inflammatory bowel disease (IBD).

本研究通过16S核糖体DNA测序（16S ribosomal DNA sequencing），同时测定了健康受试者以及腹泻、病态肥胖和炎症性肠病（IBD）患者粪便中的宏基因组群落与微生物衍生细胞外囊泡（extracellular vesicles, EVs）的特征谱。