ChIP-seq analysis for RNA polymerase II distribution in DDX41-knockdown K562 cells. Homo sapiens strain:K562

DDX41 has been implicated in RNA splicing and ribosome biosynthesis, and mutations in this gene have been found in myelodysplastic syndrome and acute myeloid leukemia. In this analysis, ChIP-seq was performed to analyze changes in RNA polymerase II distribution upon DDX41 knockdown.

DDX41已被证实参与RNA剪接与核糖体生物合成过程，该基因的突变已在骨髓增生异常综合征和急性髓系白血病中被发现。本研究采用染色质免疫共沉淀测序（ChIP-seq）技术，分析了DDX41基因敲低后RNA聚合酶II（RNA polymerase II）的分布变化。