Correlation Between Cardiac Calcium Index and Coronary Artery Disease

Resumo Introduction: Valvular deposits of calcium quantified by transthoracic echocardiography are associated with the occurrence of systemic atherosclerotic disease, but its prognostic value and influence of associated cardiovascular risk factors have not been defined yet. Objectives: To correlate the valvular cardiac calcium index by transthoracic echocardiography with cardiovascular risk factors and presence of coronary artery disease (CAD). Methods: We selected 203 patients (61.2 ± 14.3 years; 57.6% females) who underwent transthoracic echocardiography with cardiac calcium index quantification. The presence or absence of CAD, hypertension, diabetes mellitus (DM), dyslipidemia, and smoking was assessed. Results: Age above 65 years (p 65 years (OR 1.05, 95%CI 1.02-1.08, p = 0.003) correlated significantly and independently with mitral valve calcification. Aortic valve calcification alone showed no correlation with the presence of CAD (p = 0.435), but correlated significantly with age above 65 years (p

摘要：经胸超声心动图（transthoracic echocardiography）定量检测所得的瓣膜钙沉积与系统性动脉粥样硬化性疾病的发生存在关联，但目前其预后价值以及合并心血管危险因素的影响尚未明确。研究目标：探讨经胸超声心动图检测的心脏瓣膜钙指数与心血管危险因素及冠状动脉粥样硬化性心脏病（CAD）患病状态的相关性。研究方法：本研究纳入203例受试者，年龄为61.2±14.3岁，其中女性占比57.6%，所有受试者均接受了包含心脏瓣膜钙指数定量检测的经胸超声心动图检查。本研究评估了受试者是否存在冠状动脉粥样硬化性心脏病、高血压、糖尿病（DM）、血脂异常及吸烟史。研究结果：年龄超过65岁（比值比（Odds Ratio，OR）1.05，95%置信区间（95% Confidence Interval，95%CI）1.02~1.08，p=0.003）与二尖瓣钙化显著且独立相关。仅主动脉瓣钙化与冠状动脉粥样硬化性心脏病的患病状态无显著相关性（p=0.435），但与年龄超过65岁显著相关（原文内容未完整收尾）。