Pulmonary function evaluation in type 2 diabetes mellitus patients submitted to metabolic surgery

Abstract Introduction: Diabetes Mellitus (DM) is a multifactorial metabolic disorder. As considered a public health problem needing additional treatment options. Objective: This prospective study aimed at evaluating pulmonary function through spirometry, before and after metabolic surgery without gastric resection in type 2 DM patients. Methods: Sample was composed by 17 type 2 DM females. They were analyzed in pre (24 hours before surgical procedure), immediate post-operative period POST1 (24 hours after surgical procedure) and in the late postoperative period POST2 (two years after surgical procedure). Besides statistical analysis, it was evaluated the following spirometric parameters: forced vital capacity (FVC), forced expiratory volume in the first second (FEV1) and the FEV1 / FVC ratio (%). Results: Spirometric parameters showed a value increase when compared PRE and POS2 values, except for FVC and FEV1, which was not statistically significant. Conclusion: Type 2 DM women submitted to metabolic surgery without gastric resection showed spirometric value increased after two-year surgical procedure, when compared to preoperative period values. It is important additional studies about pulmonary function, diabetic patients and metabolic surgery without gastric resection.

糖尿病（Diabetes Mellitus, DM）是一种多因素代谢紊乱性疾病，被视作亟需拓展治疗手段的公共卫生问题。本前瞻性研究旨在通过肺量测定法，评估2型糖尿病患者接受非胃切除代谢手术前后的肺功能水平。研究纳入17名2型糖尿病女性受试者，分别于术前（手术前24小时）、术后即刻（POST1，术后24小时）及术后晚期（POST2，术后2年）三个时间点完成检测与分析。本研究除开展统计学分析外，同时评估了以下肺量测定参数：用力肺活量（forced vital capacity, FVC）、第一秒用力呼气容积（forced expiratory volume in the first second, FEV1）以及FEV1/FVC比值（%）。结果显示，与术前及术后2年的检测值相比，肺量测定参数整体呈升高趋势，但用力肺活量（FVC）与第一秒用力呼气容积（FEV1）的变化未达到统计学显著性水平。结论：接受非胃切除代谢手术的2型糖尿病女性患者，术后2年的肺量测定检测值较术前均有所升高。未来有必要针对糖尿病患者、非胃切除代谢手术与肺功能开展更多相关研究。