Additional file 5 of FT-GPI, a highly sensitive and accurate predictor of GPI-anchored proteins, reveals the composition and evolution of the GPI proteome in Plasmodium species

Additional file 5: Table S5. TMPred analysis of GPI-AP reference proteins. TMPred provided three parameters for each predicted TM: the first and last coordinates as well as a score. Data are presented for the first and last TM, called N-term and C-term TM respectively. The middle of the table provided information for all TM predicted in between. The distance to end parameter of the last TM was computed as the difference between the protein length and last coordinate. Proteins in bold indicate those which were positively detected by TMpred for the presence of two TM at both ends of the protein, by PredGPI for being a GPI-AP and by SignalP for the presence of a signal peptide. Missing TM and outliers with extreme TM values are in red. A. P. falciparum GPI-APs reference set. Genes with no P. vivax orthologs were in italic. B. P. vivax GPI-APs reference set. Genes with no P. falciparum orthologs are in italic.

附加文件5：表S5。GPI锚定蛋白（glycosylphosphatidylinositol-anchored protein, GPI-AP）参考蛋白的TMPred分析。针对每个预测得到的跨膜结构域（transmembrane domain, TM），TMPred均提供三项参数：其起始坐标、终止坐标以及预测得分。表格分别展示了首个与末个跨膜结构域，即N端跨膜结构域与C端跨膜结构域；表格中间区域则列出了所有介于二者之间的预测跨膜结构域的相关信息。末个跨膜结构域的“至末端距离”参数，通过蛋白质总长度与该结构域终止坐标的差值计算得到。以粗体标注的蛋白，指同时满足以下三项条件的对象：经TMpred预测在蛋白两端各存在一个跨膜结构域、经PredGPI鉴定为GPI锚定蛋白、经SignalP检测到信号肽序列。缺失跨膜结构域以及跨膜结构域数值异常的蛋白以红色标注。
A. 恶性疟原虫（*Plasmodium falciparum*）GPI锚定蛋白参考数据集。未找到间日疟原虫（*Plasmodium vivax*）同源基因的条目以斜体标注。
B. 间日疟原虫（*Plasmodium vivax*）GPI锚定蛋白参考数据集。未找到恶性疟原虫（*Plasmodium falciparum*）同源基因的条目以斜体标注。