Characteristics of thrombin activity generation curves in groups stratified on the basis of number of procoagulant alleles, with a threshold level at 5 alleles.

The analysis was performed in a subgroup of CAD patients (n = 29) without anticoagulant therapies and without signs of overt inflammation. Procoagulant alleles were fibrinogen beta-chain -455 A, Prothrombin 20210 A, Factor V Leiden, Factor V R2, Factor VII A1, Factor VII -402 A, PAI-1 -675 4G.
†: by t-test

本分析针对冠状动脉疾病（Coronary Artery Disease, CAD）患者亚组开展，共纳入29例未接受抗凝治疗且无显性炎症征象的受试者。本次分析涉及的促凝血等位基因包括：纤维蛋白原β链-455 A、凝血酶原20210 A（Prothrombin 20210 A）、莱顿第五因子（Factor V Leiden）、第五因子R2（Factor V R2）、第七因子A1（Factor VII A1）、第七因子-402 A（Factor VII -402 A）以及PAI-1 -675 4G。
†：采用t检验