Crystal structure of WDR5 in complex with peptide Ac-MRTEP-NH2

Crystal structure of WDR5 in complex with peptide Ac-MRTEP-NH2 Descriptor: ACE-MET-ARG-THR-GLU-PRO-NH2, WD repeat-containing protein 5 Authors: Min, J.-R, Zhang, M, Chen, M.-X. Deposit date: 2025-04-17 Release date: 2025-10-08 Last modified: 2025-12-10 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Therapeutic targeting of WDR5-MLL1 by EMBOW-derived peptides suppresses leukemia progression. Cell Chem Biol, 32, 2025与肽Ac-MRTEP-NH2结合的WDR5（WD重复包含蛋白5）晶体结构，描述符：ACE-MET-ARG-THR-GLU-PRO-NH2。作者：Min, J.-R、Zhang, M、Chen, M.-X. 提交日期：2025-04-17，发布日期：2025-10-08，最后修改日期：2025-12-10。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.95 Å。引用文献：《EMBOW衍生肽靶向WDR5-MLL1抑制白血病进展》，Cell Chem Biol，32卷，2025年