Crystal structure of the Lys-274 to Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD+

Protein Data Bank Japan2023-08-23 更新2026-03-21 收录

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Crystal structure of the Lys-274 to Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD+ Descriptor: NAD(P)H-dependent D-xylose reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION Authors: Leitgeb, S, Petschacher, B, Wilson, D.K, Nidetzky, B. Deposit date: 2004-12-28 Release date: 2005-02-01 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Fine tuning of coenzyme specificity in family 2 aldo-keto reductases revealed by crystal structures of the Lys-274-->Arg mutant of Candida tenuis xylose reductase (AKR2B5) bound to NAD(+) and NADP(+). FEBS Lett., 579, 2005

纤细假丝酵母（Candida tenuis）木糖还原酶（AKR2B5）Lys-274→Arg突变体结合烟酰胺腺嘌呤二核苷酸（NAD+）的晶体结构描述：依赖烟酰胺腺嘌呤二核苷酸磷酸还原型（NAD(P)H）的D-木糖还原酶、烟酰胺腺嘌呤二核苷酸、硫酸根离子作者：Leitgeb, S、Petschacher, B、Wilson, D.K、Nidetzky, B 存档日期：2004-12-28 发布日期：2005-02-01 最后更新日期：2023-08-23 实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.4埃（2.4 Å）引用文献：《结合烟酰胺腺嘌呤二核苷酸（NAD+）与烟酰胺腺嘌呤二核苷酸磷酸还原型（NADP+）的纤细假丝酵母木糖还原酶（AKR2B5）Lys-274→Arg突变体的晶体结构揭示2家族醛酮还原酶的辅酶特异性微调》，FEBS Lett., 579, 2005

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2004-12-28