Gene region candidate SNPs that exhibited signs of selection.

a T2D = Type 2 diabetes; GDM = Gestational diabetes mellitus; OB = obesity.b Significant FST, which is defined as higher than 95th percentile of FST of common SNPs in the HapMap populations.c Significant iHS assessed using coalescent simulations (see Methods). iHS has not been determined (N.D.) for SNPs with a minor allele frequency Gene region candidate SNPs that exhibited signs of selection.

a T2D即2型糖尿病（Type 2 diabetes），GDM即妊娠期糖尿病（Gestational diabetes mellitus），OB即肥胖（obesity）。b 显著性FST（Fixation Index，群体分化指数）的判定标准为：其值高于HapMap群体中常见单核苷酸多态性（Single Nucleotide Polymorphism，SNPs）的FST值的95分位数。c 经合并模拟（coalescent simulations，详见方法部分）评估得到的显著性iHS（Integrated Haplotype Score，整合单体型得分）；对于携带次要等位基因频率的单核苷酸多态性（SNPs），其iHS值尚未测定（N.D.，即Not Determined）。本研究筛选出的基因区域候选单核苷酸多态性（SNPs）均表现出选择信号。