Additional file 3 of Cord blood DNA methylome in newborns later diagnosed with autism spectrum disorder reflects early dysregulation of neurodevelopmental and X-linked genes

Additional file 3: Table S25. DMB gene functional enrichment for all comparisons. Table S26. DMR gene functional enrichment for all comparisons. Table S27. DMR gene functional enrichment for all comparisons with conservative mapping. Table S28. X-linked gene functional enrichment. Table S29. DMR gene ASD study enrichment for all comparisons. Table S30. DMR gene ASD study enrichment for all comparisons with conservative mapping. Table S31. Histone PTM and chromatin state enrichment for all, autosomal, and X-linked discovery males DMRs. Table S32. Histone PTM and chromatin state enrichment for all, autosomal, and X-linked discovery females DMRs. Table S33. Histone PTM and chromatin state enrichment for all, autosomal, and X-linked replication males DMRs. Table S34. Histone PTM and chromatin state enrichment for all, autosomal, and X-linked replication females DMRs. Table S35. CpG context enrichment for all, autosomal, and X-linked DMRs from all comparisons. Table S36. Transcription factor motif enrichment for all, autosomal, and X-linked DMRs from all comparisons. Table S37. Fetal Brain ChromHMM enrichment for top transcription factor motifs. Table S38. Post hoc power analysis.

附加文件3：表S25。所有比较组的DMB基因功能富集分析。表S26。所有比较组的DMR（差异甲基化区域，Differentially Methylated Region）基因功能富集分析。表S27。采用保守映射策略的所有比较组的DMR基因功能富集分析。表S28。X连锁基因功能富集分析。表S29。所有比较组的DMR基因孤独症谱系障碍（Autism Spectrum Disorder, ASD）研究富集分析。表S30。采用保守映射策略的所有比较组的DMR基因孤独症谱系障碍研究富集分析。表S31。所有、常染色体及X连锁发现集男性DMR的组蛋白翻译后修饰（Histone Post-translational Modification, PTM）与染色质状态富集分析。表S32。所有、常染色体及X连锁发现集女性DMR的组蛋白翻译后修饰与染色质状态富集分析。表S33。所有、常染色体及X连锁验证集男性DMR的组蛋白翻译后修饰与染色质状态富集分析。表S34。所有、常染色体及X连锁验证集女性DMR的组蛋白翻译后修饰与染色质状态富集分析。表S35。所有比较组来源的涵盖全基因组、常染色体及X连锁DMR的CpG上下文富集分析。表S36。所有比较组来源的涵盖全基因组、常染色体及X连锁DMR的转录因子基序富集分析。表S37。顶级转录因子基序的胎儿大脑ChromHMM富集分析。表S38。事后效力分析。