Identification of circRNAs associated with inosinic acid-specific deposition in muscle of Jingyuan chicken

Skeletal muscle supports the normal life activities of livestock and poultry and is important source of human nutrition. Poultry is an essential short-cycle, inexpensive source of high-quality protein. The development of skeletal muscle in poultry is regulated by various factors, including genetics, nutrition, disease, and environment, and genetic selection, and breeding is an effective long-term solution to skeletal muscle growth and development in poultry. The genetic factors controlling skeletal muscle development include genes and non-coding RNAs. Circular RNAs (circRNAs) are key gene regulators that are involved in many muscles development processes.

骨骼肌（Skeletal muscle）是畜禽维持正常生命活动的重要组织，同时也是人类获取营养的关键来源。家禽是不可或缺的短周期、低成本优质蛋白质来源。家禽骨骼肌的发育受遗传、营养、疾病与环境等多种因素调控；而遗传选育是改善家禽骨骼肌生长发育的长效有效手段。调控骨骼肌发育的遗传因素包括编码基因与非编码RNA（non-coding RNAs）。环状RNA（Circular RNAs，circRNAs）是一类关键的基因调控因子，参与众多肌肉发育过程。