Corynebacterium striatum prosthetic joint infection successfully treated with long-term dalbavancin

Arthroplasty surgery is a common procedure that significantly improves quality of life. The most feared complication is prosthetic joint infection, which occurs more often following revision surgery. Staphylococci are the most prevalent bacteria in PJIs, although many other pathogens have been reported. We describe a case of PJI in a 75 year old farmer following revision surgery, caused by Corynebacterium striatum, an unusual agent which normally occurs in the normal hu-man skin microbiota with perceived low pathogenicity.

关节置换手术（Arthroplasty）是一类可显著改善患者生活质量的常规临床术式。其中最令人担忧的并发症为人工关节感染（Prosthetic Joint Infection, PJI），该病症在关节翻修手术后的发生率更高。尽管已有诸多其他病原菌的相关报道，但葡萄球菌（Staphylococci）仍是人工关节感染中最为常见的致病菌。本研究报道1例75岁农民在关节翻修术后发生人工关节感染的病例，其致病病原菌为纹状棒状杆菌（Corynebacterium striatum）——一种通常定植于人体正常皮肤菌群、既往被认为致病性较低的罕见致病菌。