Becoming a mother shifts the activity of the social and motivation brain networks in mice

Data from two experiments are provided.

EXPERIMENT 1. cFos expression in the Socio-Motivational Brain Network in females exposed to pups or buttons; data on pup-elicited behaviours are also provided.

Two kinds of females (Virgin or Late Pregnant - LP) were exposed to one of two stimulus (3-day old Pups or Buttons). This is a classic 2x2 experimental design.

Each animal occupies a ROW.

COLUMNS indicate:
- Animal code, female class, stimulus it was exposed to
- Data on the different behavioural items registered, or the scores calculated (see STAR Methods)
- Density of cells (per square mm of tissue sampled) positive for cFos in the different nuclei of the sociosexual brain network (SBN)
- Density of cells (per square mm of tissue sampled) positive for cFos in the different nuclei of the Motivation Brain Circuit

These data have been used for Figures 1-3 and, after processing, for the rest of the figures of the paper.
Behavioural data were used for Table S1 and, after processing, for Tables S2 and S3 and Figure S2.

EXPERIMENT 2. Button-elicited behaviours in Virgin and Late Pregnant females
Two kinds of females (Virgin or Late Pregnant - LP) were exposed to buttons. The experimental design mimics the previous experiment.

Each animal occupies a ROW.

COLUMNS indicate:
- Animal code, female class
- Number of episodes of sniffing at the buttons during the test
- Total time sniffing buttons
- Number of episodes of interacting with the homecage mate female
- Total time sniffing at the homecage mate female

These data have been used for Figure S1

本数据集包含两项实验的相关数据。

实验1：暴露于幼崽或按钮的雌性个体社会动机脑网络（Socio-Motivational Brain Network）内cFos蛋白表达情况，同时附带幼崽诱导行为相关数据。
本实验采用经典2×2实验设计，设置两类受试雌性个体：未生育处女雌性（Virgin）与妊娠晚期（Late Pregnant, LP）雌鼠，将其分别暴露于两种刺激物——3日龄幼崽或按钮——中。
每条记录对应一只受试动物，以行表示。列所涵盖的信息如下：
- 动物编号、受试雌性类别、所暴露的刺激物类型
- 所记录的各类行为条目数据，或经计算得到的行为得分（详见STAR 方法（STAR Methods））
- 社会性行为脑网络（Sociosexual Brain Network, SBN）不同脑核团中cFos阳性细胞密度（单位：每平方毫米取样组织）
- 动机脑环路不同脑核团中cFos阳性细胞密度（单位：每平方毫米取样组织）

本部分数据已用于制作图1至图3，经进一步处理后用于该论文其余所有图表。其中行为学数据已用于补充表S1，经处理后用于补充表S2、S3及补充图S2。

实验2：处女雌性与妊娠晚期雌鼠的按钮诱导行为
本实验设置两类受试雌性个体：未生育处女雌性与妊娠晚期雌鼠，仅将其暴露于按钮刺激物中，实验设计参照前述实验。
每条记录对应一只受试动物，以行表示。列所涵盖的信息如下：
- 动物编号、受试雌性类别
- 测试期间嗅探按钮的行为事件次数
- 嗅探按钮的总时长
- 与笼内同伴雌性互动的行为事件次数
- 嗅探笼内同伴雌性的总时长

本部分数据已用于制作补充图S1。