Congestion and fibrosis in intact and ovariectomized (OVX) mice receiving either 0 or 16 Gy radiation 30 days previously.

Semi-quantitative estimates performed by a board certified veterinary clinical pathologist (LS) according to standard protocols. Cells contain the data for individual mice (n = 5/group). Numerical scale: −4 severely decreased, −3 markedly decreased, −2 moderately decreased, −1 mildly decreased, +1 mildly increased, +2 moderately increased, +3 markedly increased, +4 severely increased, normal assigned a value of 0 for statistical calculations. Wilcoxon rank-sum test:*Radiation exposure significantly increased congestion compared with non-irradiated (p = 0.0495),†Radiation significantly increased fibrosis compared with non-irradiated (p = 0.0143). Note that ovarian hormonal status did not separately affect either parameter.

本数据集的半定量评估由认证兽医临床病理学家LS依照标准实验方案完成。数据单元格中记录了每只实验小鼠的检测数据，每组小鼠数量为5只（n=5/group）。数值评分规则如下：-4代表严重降低，-3为显著降低，-2为中度降低，-1为轻度降低；+1为轻度升高，+2为中度升高，+3为显著升高，+4为严重升高；正常生理状态在统计计算中统一赋值为0。威尔科克森秩和检验（Wilcoxon rank-sum test）结果显示：*辐射照射组的充血程度显著高于未照射组（p=0.0495）；†辐射照射组的纤维化程度显著高于未照射组（p=0.0143）。需注意，卵巢激素状态未对上述两项指标分别产生独立影响。