Standardizing the injection point distance in palmar hyperhidrosis treatment using 3D printed molds.

The use of a 3D printed acrylonitrile butadiene styrene (ABS) mold with a regular conical pattern and a 1 cm distance between each cone spike. A pack of gauzes is soaked in povidone iodine solution that will work as an ink pad. The sharp-pointed aspect of the mold will be pressed on the impregnated gauzes and subsequently stamped onto the affected area to treat (Fig 1). This ensures that the treatment area receives an equally distributed quantity of BTX. Not only does this method provide standardization of the distance between injections, but it also represents an efficient time-sparing technique. Additionally, iodine povidone marks are easier to clean (for example, with saline or chlorhexidine solutions) than those produced with conventional marker pens. Finally, this solution could also be useful in other injected treatments such as corticosteroids in alopecia areata or dutasteride in androgenetic alopecia. A Supplementary Video showing the full procedure is available.

本研究使用带有规则锥形图案、锥尖间距为1厘米的3D打印丙烯腈-丁二烯-苯乙烯（acrylonitrile butadiene styrene, ABS）模具。将一包纱布浸泡于聚维酮碘溶液中作为印台。将模具的尖锐锥面按压在浸有该溶液的纱布上，随后按压至患处实施治疗（图1）。此举可确保治疗区域获得分布均匀的肉毒杆菌毒素（botulinum toxin, BTX）。该方法不仅实现了注射间距的标准化，同时也是一种高效省时的操作技术。此外，聚维酮碘留下的印记相较于传统记号笔的印记更易清洁，例如可使用生理盐水或氯己定溶液擦拭。最后，该方案还可应用于其他注射治疗场景，如斑秃的糖皮质激素注射或雄激素性脱发的度他雄胺注射。附带展示完整操作流程的补充视频可供获取。