Next Generation Sequencing of isolated EGFR+ and HLA-G+ first trimester human trophoblasts

The aim of this study was to identify differentially expressed signatures of non-invasive (EGFR+) and invasive (HLA-G+) human trophoblast subtypes. These populations were isolated from single first trimester placentas from 10-12 weeks of gestation. We performed RNAseq to analyze the global expression profile of two different trophoblastic subtypes.

本研究旨在鉴定非侵袭性（EGFR+）与侵袭性（HLA-G+）人滋养层细胞亚型的差异表达特征。所研究的细胞群分离自孕10-12周的单个妊娠早期胎盘组织。我们通过RNA测序（RNAseq）分析了两种不同滋养层细胞亚型的全局表达谱。