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Additional file 4 of Sequential drug treatment targeting cell cycle and cell fate regulatory programs blocks non-genetic cancer evolution in acute lymphoblastic leukemia

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NIAID Data Ecosystem2026-05-02 收录
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https://figshare.com/articles/dataset/Additional_file_4_of_Sequential_drug_treatment_targeting_cell_cycle_and_cell_fate_regulatory_programs_blocks_non-genetic_cancer_evolution_in_acute_lymphoblastic_leukemia/26728366
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Additional file 4. Table S4 scATAC summary of significantly different motif access across clusters. RS4;11 24 h AZD1775 and DMSO chromVar analysis results. Significantly differentially active motifs used for clustering. Based on statistical comparison of AZD1775 and DMSO chromatin states (data sheets chromatin state 1-6), and DMSO chromatin state 1-5, p-value from Wilcoxon Rank Sum test is shown.

附加文件4:表S4 跨聚类显著差异基序可及性的单细胞转座酶可及性染色质测序(single-cell Assay for Transposase-Accessible Chromatin using sequencing, scATAC)分析汇总。本数据集包含RS4;11细胞经AZD1775处理24小时与二甲基亚砜(Dimethyl sulfoxide, DMSO)对照组的chromVar分析结果。其中,用于聚类分析的显著差异活性基序,基于AZD1775处理组与DMSO对照组的染色质状态(对应数据表中染色质状态1至6)以及DMSO对照组染色质状态1至5的统计学比较,展示了Wilcoxon秩和检验(Wilcoxon Rank Sum test)得到的P值。
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2024-05-31
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