Best single genes and their impacts for the = 1 and = 2 models.

The unconstrained (UNC) and constrained (CON) case are shown. The constrained case refer to target that are kinases and are expressed in the cancer case. I = IMR-90 (normal), A = A549 (cancer), H = NCI-H358 (cancer), N = Naïve (normal), M = Memory (normal), D = DLBCL (cancer), F = Follicular lymphoma (cancer), L = EBV-immortalized lymphoblastoma (cancer).Best single genes and their impacts for the = 1 and = 2 models.

本研究展示了无约束（unconstrained，UNC）与约束（constrained，CON）两种实验场景。其中约束场景特指靶点为激酶且在癌症样本中存在表达的情况。各样本标识的含义如下：I代表IMR-90正常细胞，A代表A549癌细胞，H代表NCI-H358癌细胞，N代表未致敏正常细胞，M代表记忆正常细胞，D代表弥漫大B细胞淋巴瘤（DLBCL）癌细胞，F代表滤泡淋巴瘤癌细胞，L代表EBV永生化淋巴母细胞瘤癌细胞。此外，还给出了针对取值为1与取值为2的模型的最优单基因及其作用影响。