Additional file 6: of Transcriptional analysis of abdominal fat in chickens divergently selected on bodyweight at two ages reveals novel mechanisms controlling adiposity: validating visceral adipose tissue as a dynamic endocrine and metabolic organ

Top pathways and biological functions identified by IPA from time-course microarray analysis of abdominal fat in HG and LG cockerels (1-11 wk). A Microsoft Excel file containing eight worksheets [i.e., “Upstream Regulators, Oxidative Phosphorylation, LXR/RXR Activation, Fatty Acid Metabolism, Adipogenesis Pathway, Insulin Resistance, VEGF Signaling, and Protein Metabolism”]. Top canonical pathways and biological functions were identified by Ingenuity Pathway Analysis (IPA) of 647 “Analysis Ready” (AR)-DE genes (FDR ≤ 0.05) from time-course (1-11 wk) microarray analysis. (XLSX 49 kb)

本数据集源自对高生长（HG）与低生长（LG）公鸡1~11周龄腹部脂肪的时序微阵列分析，经Ingenuity通路分析（Ingenuity Pathway Analysis）鉴定得到核心经典通路与生物学功能。本数据集以Microsoft Excel文件形式存储，内含8个工作表，分别为：上游调控因子（Upstream Regulators）、氧化磷酸化（Oxidative Phosphorylation）、LXR/RXR激活（LXR/RXR Activation）、脂肪酸代谢（Fatty Acid Metabolism）、成脂通路（Adipogenesis Pathway）、胰岛素抵抗（Insulin Resistance）、VEGF信号通路（VEGF Signaling）以及蛋白质代谢（Protein Metabolism）。本次分析的基因集为647个经时序（1~11周龄）微阵列分析得到的「分析就绪（Analysis Ready, AR）」差异表达基因（differentially expressed genes, DE genes），其错误发现率（False Discovery Rate, FDR）≤0.05，通过上述分析鉴定得到核心经典通路与生物学功能。本数据集文件格式为XLSX，大小为49 KB。