Osteosarcoma of the hard palate in a dog ˗ case report

ABSTRACT The osteosarcoma (OSA) is the most diagnosed primary bone cancer in canine patients. This work reports a case of a canine, six years old, mongrel, female, intact, with an OSA in the hard palate. Physical examination detected a firm mass in the palate. Thoracic radiographs, hematological and biochemical exams, histopathological exams and computed tomography were requested. A chondroblastic OSA was diagnosed and the tumor was characterized by immunohistochemistry. There was never evidence of metastasis in this case. The treatment consisted of the combination of conventional chemotherapy, metronomic chemotherapy, and palliative care, aiming at greater survival and well-being of the patient since surgical excision was not possible due to the location and extension of the tumor. Osteogenic sarcomas of the hard palate are rarely seen and described in the literature. In this article we present a characterization of the osteosarcoma with uncommon localization in the hard palate.

摘要：骨肉瘤（osteosarcoma, OSA）是犬类患者中诊断率最高的原发性骨肿瘤。本研究报告一例6岁未绝育雌性杂种犬的硬腭骨肉瘤病例。体格检查发现其腭部存在硬性肿块，随后完善了胸部X光片拍摄、血液学与生化检查、组织病理学检查以及计算机断层扫描（computed tomography, CT）。经免疫组织化学检测确诊为软骨母细胞型骨肉瘤，并对肿瘤进行了特征分析。本病例未出现转移征象。由于肿瘤的位置与侵袭范围无法实施手术切除，故采用常规化疗联合节律化疗与姑息治疗方案，以期延长患犬生存时间并提升其生活质量。硬腭骨肉瘤在临床中较为罕见，相关文献报道较少，本文旨在对一例发生于硬腭这一罕见部位的骨肉瘤进行特征阐述。