Transcriptomic analysis of female sharpbelly (Hemiculter lucidus) in Ba River

This work aimed at predicting the toxic effects of phenolic compounds in Ba River on the health of female sharpbelly (Hemiculter lucidus) by the de novo transcriptomic analysis of the liver. Sharpbelly, a native fish living in freshwater ecosystem of East Asia, were sampled upstream, near, and downstream of a wastewater discharge to the Ba river. Based on the occurrence of bisphenol A (BPA), nonylphenol (NP), and 4-tert-octylphenol (4-t-OP) in the water and fish sampled from each site, up-, mid-, and down-stream were interpreted as control, high, and low treatment groups, respectively.

本研究通过肝脏的从头转录组学分析，旨在预测巴河酚类化合物对雌性餐条鱼（Hemiculter lucidus）健康的毒性效应。餐条鱼为栖息于东亚淡水生态系统的本土鱼类，本研究在巴河一处排污口的上游、紧邻排污口区域及下游开展采样。基于各采样点水体及鱼体中双酚A（BPA）、壬基酚（NP）与4-叔辛基酚（4-t-OP）的检出情况，将上游、中游、下游分别设为对照组、高暴露组与低暴露组。