Vogt-Koyanagi-Harada syndrome: evaluation of the disease phase in which patients receive the first specialized attendance

Abstract Objective: To evaluate in which phase of Vogt-Koyanagi-Harada (VKH) syndrome the patients receive the first attendance in specialized service. Methods: A retrospective study was conduted to evaluate medical records of 14 patients with VKH in the Clementino Fraga Filho University Hospital of the Federal University of Rio de Janeiro from January 2014 to March 2017. In this analysis, gender, age, stage of disease and visual acuity of these patients with at least probable VKH were recorded. Results: Of these patients, 78.5% were female and 21.5% male and the median age was 34 years. We observed that 35.4% of the patients had the disease still in the uveitic phase and that 78.5% of these patients had visual acuity equal to or worse than 0.05. Conclusion: There is a delay in the admission of these patients to a specialized sector, thus affecting directly the treatment and visual prognosis.

摘要
研究目的：探讨伏格特-小柳-原田（Vogt-Koyanagi-Harada，VKH）综合征患者首次就诊于专科医疗服务机构时所处的疾病分期。
研究方法：本研究为回顾性研究，纳入2014年1月至2017年3月期间，里约热内卢联邦大学克莱门蒂诺·弗拉加·菲略大学附属医院收治的14例VKH综合征患者的病历资料进行分析。本次分析中，我们记录了至少符合疑似VKH诊断标准的患者的性别、年龄、疾病分期及视力情况。
研究结果：本研究纳入的患者中，78.5%为女性，21.5%为男性，中位年龄为34岁。我们观察到，35.4%的患者就诊时疾病仍处于葡萄膜炎期，且其中78.5%的患者视力≤0.05。
研究结论：此类患者首次就诊于专科医疗机构存在延迟，这将直接影响治疗效果与视力预后。