Additional file 2 of The landscape of human tissue and cell type specific expression and co-regulation of senescence genes

Additional file 2: Table S1. The SnG-enriched modules in 50 human tissues. Table S2. The k-means clusters of SnGs. Table S3. The k-means clusters of SnG-enriched modules. Table S4. The conserved 3-layer neighborhood of CDKN1A in the co-expression networks. Table S5. The conserved 3-layer neighborhood of TP53 in the co-expression networks. Table S6. The aggregated network of SnG-enriched modules. Table S7. The SASP factors from the aggregated network and their regulations by senescence and CDKN1A. Table S8. The cell types enriched (FDR < 0.01) for each SnG-enriched module. Table S9. The age correlation of aggregated network genes. Table S10. The modules M81 and M82 in the brain hippocampus. Table S11. Gene coexistence proportion between senescence markers and aggregated network genes in single brain cells. Table S12. The module M6 in the testis. Table S13. Gene coexistence proportion between senescence markers and aggregated network genes in single testis cells. Table S14. The Cell communications between pancreas ductal cells and other cell types.

附加文件2：表S1。50种人体组织中富集SnG的模块。表S2：SnGs的k-means聚类簇。表S3：富集SnG的模块的k-means聚类簇。表S4：共表达网络中CDKN1A的保守3层邻域。表S5：共表达网络中TP53的保守3层邻域。表S6：富集SnG的模块的聚合网络。表S7：聚合网络来源的衰老相关分泌表型（Senescence-Associated Secretory Phenotype, SASP）因子及其受衰老与CDKN1A的调控关系。表S8：每个富集SnG的模块所富集的细胞类型（错误发现率False Discovery Rate, FDR < 0.01）。表S9：聚合网络基因的年龄相关性。表S10：大脑海马体中的M81与M82模块。表S11：单个脑细胞中衰老标志物与聚合网络基因的基因共存比例。表S12：睾丸中的M6模块。表S13：单个睾丸细胞中衰老标志物与聚合网络基因的基因共存比例。表S14：胰腺导管细胞与其他细胞类型间的细胞通讯。