Preparation of Allenephosphoramide and Its Utility in the Preparation of 4,9-Dihydro-2H-benzo[f]isoindoles

Allenephosphoramides were prepared from propargyl alcohols and diethyl arylphosphoramides using Yb(OTf)3 as catalyst. In the presence of iodine, 4,9-dihydro-2H-benzo[f]isoindole derivatives could be efficiently constructed from the same two starting materials in a single step.

以三氟甲磺酸镱（Yb(OTf)₃）为催化剂，可由炔丙醇与二乙基芳基磷酰胺制备联烯磷酰胺（Allenephosphoramides）。在碘单质存在下，上述两种起始原料可经一步法高效构建4,9-二氢-2H-苯并[f]异吲哚衍生物。