A SQUAMOUS CELL CARCINOMA OF THE UTERINE CERVIX RECURRING IN THE FORM OF AN ISOLATED BLADDER METASTASIS: A CASE REPORT AND REVIEW OF THE LITERATURE

Bladder cancer is the second most common urological cancer after prostate cancer, and bladder metastases are rare. We report the case of a 42-year-old female patient who underwent surgical treatment for cervical cancer 5 years ago and presented with a recurrence of her disease in the form of an isolated bladder tumor resembling primary bladder cancer. The diagnosis was confirmed by human papillomavirus (HPV) genotyping performed on the biopsy sample of the bladder tumor. The patient was treated with chemotherapy similar to that used for cervical cancer, with a favorable clinical and biological response.

膀胱癌是仅次于前列腺癌的第二常见泌尿系统恶性肿瘤，且膀胱转移瘤较为罕见。本文报告1例5年前因宫颈癌接受手术治疗的42岁女性患者，其病情复发表现为孤立性膀胱肿瘤，外观与原发性膀胱癌相似。通过对该膀胱肿瘤的活检样本进行人乳头瘤病毒（human papillomavirus, HPV）基因分型检测，明确了该诊断。患者接受了与宫颈癌化疗方案一致的化学治疗，获得了良好的临床及生物学应答。