Three-Component [2+2+1] Cross-cyclotrimerization of Carboryne, Unactivated Alkene, and Trimethylsilylalkyne Co-mediated by Zr and Ni

A three-component [2+2+1] cross-cyclotrimerization of carboryne, alkene, and trimethylsilylalkyne has been achieved under the cooperative action of zirconium and nickel, leading to the synthesis of a series of dihydrofulvenocarboranes. The bulkiness of the alkyne and phosphine ligand plays a key role in the selective formation of the products.

在锆（zirconium）与镍（nickel）的协同作用下，本研究实现了碳硼炔（carboryne）、烯烃（alkene）与三甲基硅基炔烃（trimethylsilylalkyne）的三组分[2+2+1]交叉环三聚反应，进而合成了一系列二氢富烯碳硼烷（dihydrofulvenocarboranes）类化合物。炔烃与膦配体（phosphine ligand）的空间位阻效应，对产物的选择性生成起到关键作用。