Transcriptome analysis of equine sarcoids. Equus caballus

The aim of this study was to identify changes in transcriptome of horse sarcoids - a locally invasive skin tumors of equids, which are considered to be the most common equine skin neoplasm. The global expression of genes was investigated in four tumour samples and in the tumour-distant skin samples, obtained from the same individual. Overall design: One-condition experiment, sarcoid vs. tumour-distant skin. Biological replicates: 4 sarcoid replicates, 4 control tissue replicates.

本研究旨在明确马肉瘤（horse sarcoids）——一种具有局部侵袭性的马科动物皮肤肿瘤，亦是目前公认的最为常见的马类皮肤肿瘤——的转录组（transcriptome）变化。本研究对4份肿瘤样本及取自对应宿主的瘤远隔皮肤样本开展了全基因表达谱分析。实验设计：单因素实验，即马肉瘤组与瘤远隔皮肤对照组。生物学重复：马肉瘤组设置4个生物学重复，对照组织组设置4个生物学重复。