A table summarising the fitness and lethality parameters used throughout this study.

Within the mathematical model numbers of each transgenic construct carried by a particular genotype (i) are denoted and for transgenic constructs A and B, respectively. Also shown within this table are the lethality parameters (γi) used to define each of the gene drive elements with γ = 1 representing 100% effective lethality whilst γ = 0 denotes a viable genotype. Here the different gene drives considered are denoted UD (engineered underdominance) and KR (killer-rescue) with SS and WS representing strong and weak suppression of lethals, respectively. Here strong suppression of lethals refers to the scenario whereby one copy of a suppressor transgene is sufficient to rescue against two copies of the associated lethal transgene, whereas for weak suppression two suppressor copies are required to save against two lethal copies. For killer-rescue constructs, parameter values were selected such that construct A represents the killer and B the rescue.

特定基因型(i)所携带的各转基因构建体（transgenic construct）的数学模型编号，分别以转基因构建体A和B进行标注。本表同时列出了用于定义各基因驱动元件的致死参数(γᵢ)：当γ=1时代表100%有效致死，而γ=0则代表基因型存活。本研究考虑的不同基因驱动（gene drive）分别记为UD（engineered underdominance，即工程化劣势效应）和KR（killer-rescue，即杀伤-救援系统）；其中SS和WS分别代表对致死因子的强抑制与弱抑制。其中，对致死因子的强抑制指的是：仅需1个抑制性转基因（suppressor transgene）拷贝，即可抵消2个相关致死转基因（lethal transgene）拷贝所引发的致死效应；而弱抑制则需要2个抑制性转基因拷贝，才能抵消2个致死转基因拷贝所引发的致死效应。针对杀伤-救援型转基因构建体，参数取值被设定为：构建体A代表杀伤元件，构建体B代表救援元件。