SH1426934.10FU

UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.

UNITE为界定、识别、传播及开展基于DNA的物种假说（Species Hypotheses, SH）相关工作提供了统一的实现路径。国际核苷酸序列数据库中的所有真菌ITS序列，均通过采用一系列动态距离阈值（0.5%~3.0%）进行聚类，最终形成近似物种级别的聚类簇。所有物种假说均会被赋予一个以数字对象标识符（Digital Object Identifier, DOI）为形式的唯一且稳定的名称，其分类学与生态学注释信息将通过分布式、基于网页的第三方注释工作进行核验。通过整合该物种假说所包含的全部序列的鉴定信息，尽可能为其匹配对应的分类单元名称及其所属的分类层级（如门、纲、目等）。将选取一条经自动或人工指定的序列作为该物种假说的代表序列。上述代表序列已通过https://unite.ut.ee/repository.php公开发布，可供科研社区用于本地序列相似性搜索、下一代测序分析流程等场景。随着公共真菌ITS序列数量的不断增长，该系统及其所包含的数据将自动进行更新。