Modular microenvironment components reproduce vascular dynamics de novo in a multi-scale agent-based model: ESTIMATED HEMODYNAMICS

Data and results for `ESTIMATED HEMODYNAMICS` simulations.

Simulations of cancerous cells in colony and tissue contexts with estimated hemodynamics varying different hemodynamic factors (concentration gradient, local consumption, and upstream flow) with weights from 0 to 20 in increments of 1. Each condition is run for 15 days (21600 ticks) with 10 replicates (random seeds 0 - 9). Cancerous cells (max_height x 1.5, meta_pref x 1.5, migra_threshold x 0.5) are introduced to the center of the environment after a 1 day delay. Snapshots are taken every 0.5 days (720 ticks). The data folder contains .tar.xz compressed replicate sets. The results folder contains .pkl files of data parsed into arrays. Simulations are labeled as: [context]_[factor]_[weight]

- [context]
- C = colony context, cancerous cells only
- CH = tissue context, cancerous cells and healthy cells
- [factor]
- weight_gradient = concentration gradient factor
- weight_local = local consumption factor
- weight_flow = upstream flow factor
- [weight]
- ### = factor weight (###/10)

本数据集为`ESTIMATED HEMODYNAMICS`（预估血流动力学）模拟相关的数据与结果。

本数据集包含集落与组织环境中的癌细胞模拟实验，通过调整不同血流动力学参数（浓度梯度、局部消耗与上游流量）的权重（取值范围0至20，步长为1）来控制预估血流动力学状态。每个实验条件均运行15天（对应21600个时间步），并设置10次重复实验（随机种子取值为0至9）。在延迟1天后，将参数调整为`max_height ×1.5`、`meta_pref ×1.5`、`migra_threshold ×0.5`的癌细胞接种至实验环境的中心位置。每0.5天（对应720个时间步）采集一次系统快照。

数据文件夹中存储了经`.tar.xz`格式压缩的重复实验数据集；结果文件夹中存储了解析为数组格式的`.pkl`格式数据文件。模拟实验的命名规则为：[实验环境]_[参数类型]_[权重值]
- [实验环境]
- C：集落环境，仅包含癌细胞
- CH：组织环境，包含癌细胞与健康细胞
- [参数类型]
- weight_gradient：浓度梯度参数权重
- weight_local：局部消耗参数权重
- weight_flow：上游流量参数权重
- [权重值]
- ###：参数权重，实际取值为###/10