Additional file 1 of The SF3B1R625H mutation promotes prolactinoma tumor progression through aberrant splicing of DLG1

Additional file 1: Table S1. Primers used for qRT-PCR in this study. Table S2. The clinical data of 15 prolactinoma patients. Table S3. siRNA used in this study. Table S4. Antibodies used in this study. Table S5. Differentially expressed gene in Sf3b1 mutant GH3 cells. Table S6. Differentially expressed gene in SF3B1 mutant human prolactinoma. Table S7. Significant alternative splicing events in Sf3b1 mutant GH3 cells. Table S8. Gene Ontology (GO) function of AS genes in Sf3b1 mutant GH3 cells. Table S9. Significant alternative splicing events in SF3B1 mutant human prolactinoma. Table S10. Gene Ontology (GO) function of AS genes in SF3B1 mutant human prolactinoma. Table S11. Gene Ontology (GO) function of differentially expressed genes in Sf3b1 mutant GH3 cells. Table S12. KEGG pathway analysis of differentially expressed genes in Sf3b1 mutant GH3 cells. Table S13. KEGG pathway analysis of differentially expressed genes in SF3B1 mutant human prolactinoma.

附加文件1：表S1。本研究中用于定量实时聚合酶链反应（quantitative real-time polymerase chain reaction，qRT-PCR）的引物。表S2。15例泌乳素瘤患者的临床资料。表S3。本研究中使用的小干扰RNA（small interfering RNA，siRNA）。表S4。本研究中使用的抗体。表S5。Sf3b1突变GH3细胞中的差异表达基因。表S6。SF3B1突变人泌乳素瘤中的差异表达基因。表S7。Sf3b1突变GH3细胞中的显著可变剪接事件。表S8。Sf3b1突变GH3细胞中可变剪接（alternative splicing，AS）基因的基因本体（Gene Ontology，GO）功能注释。表S9。SF3B1突变人泌乳素瘤中的显著可变剪接事件。表S10。SF3B1突变人泌乳素瘤中可变剪接（AS）基因的基因本体（GO）功能注释。表S11。Sf3b1突变GH3细胞中差异表达基因的基因本体（GO）功能注释。表S12。Sf3b1突变GH3细胞中差异表达基因的京都基因与基因组百科全书（Kyoto Encyclopedia of Genes and Genomes，KEGG）通路分析。表S13。SF3B1突变人泌乳素瘤中差异表达基因的京都基因与基因组百科全书（KEGG）通路分析。