FAIRsharing record for: Transcription Factor Class

This FAIRsharing record describes: TFClass is a resource that classifies eukaryotic transcription factors (TFs) according to their DNA-binding domains. Combining information from different resources, manually checking the retrieved mammalian TF sequences and applying extensive phylogenetic analyses, >39,000 TFs from up to 41 mammalian species were assigned to the Superclasses, Classes, Families and Subfamilies of TFClass. TFClass provides corresponding sequence collections in FASTA format; sequence logos and phylogenetic trees at different classification levels; predicted TF binding sites for human, mouse, dog and cow genomes; and links to several external databases.

本FAIRsharing记录描述：TFClass是一个基于DNA结合结构域对真核生物转录因子（TFs）进行分类的资源。通过整合多源信息、手动校验检索到的哺乳动物TF序列，并应用全面的系统发育分析，来自至多41个哺乳动物物种的39000余个TF被归入TFClass的超类、类、家族及亚家族等级别。TFClass提供以下资源：FASTA格式的对应序列集合；不同分类层级的序列标志（sequence logos）及系统发育树；人类、小鼠、犬和牛基因组的预测TF结合位点；以及若干外部数据库的链接。