Developmental programming in Idiopathic pulmonary fibrosis (IPF). Homo sapiens

Global mRNA expression was compared between stable and progressive IPF using bronchoalveolar lavage derived mesenchymal stromal cells Overall design: Stable and progressive IPF patients were identified by a decline in forced vital capacity (FVC) < 5% and FVC ≥ 10% respectively over preceding 6 months

本研究以支气管肺泡灌洗液来源的间充质基质细胞（bronchoalveolar lavage derived mesenchymal stromal cells）为研究材料，比较稳定型与进展型特发性肺纤维化（idiopathic pulmonary fibrosis, IPF）患者的全局mRNA表达谱差异。
实验设计概述：根据受试患者前6个月内的用力肺活量（forced vital capacity, FVC）下降幅度区分分型：FVC下降幅度<5%者归类为稳定型IPF患者，下降幅度≥10%者则为进展型IPF患者。