Recognition of Polyfluorinated Compounds Through Self-Aggregation in a Cavity

Polyfluorinated
aliphatic compounds were encapsulated by a self-assembled M6L4 coordination host in aqueous media. NMR titration and
X-ray crystallographic analyses clearly revealed that the aggregation
of the fluorinated moieties of the guests in the host cavity plays
a significant role in the binding. Polyfluorinated aromatics did not
show such aggregation in the cavity because of their “nonfluorous” nature.

在水相介质中，自组装制备的M₆L₄型配位主体（coordination host）可包封多氟化脂肪族化合物。核磁共振滴定（NMR titration）与X射线晶体学分析明确揭示，客体分子的氟化基团在主体空腔内的聚集行为对该结合过程具有显著作用。多氟化芳香族化合物因具备非氟性（nonfluorous）的性质，无法在主体空腔中形成此类聚集。