CNV - Bos indicus (Nelore) raw sequence reads

DNA from eight unrelated Nelore founding bulls was resequenced using Illumina HiSeq2000 paired-end reads. CNVs were detected using LUMPY, a novel CNV discovery framework that uses multiple detection signals including read depth from split reads and mis-mapped paired ends.

本研究对8只无亲缘关系的内洛尔牛种公牛的基因组DNA进行了重测序，测序采用Illumina HiSeq2000平台的双端测序读段。随后，研究采用LUMPY工具开展拷贝数变异（Copy Number Variations, CNVs）检测；该工具为一款新型CNV检测框架，可整合分裂读段测序深度、错配双端读段等多种检测信号。