Respiratory Syncytial virus (RSV) directly binds host microRNAs and de-regulates host gene targets [RNA-seq]. Respiratory Syncytial virus (RSV) directly binds host microRNAs and de-regulates host gene targets [RNA-seq]

To investigate RNA expression changes in RSV infection, we performed total RNA-seq from Mock and RSV-infected A549 cells In addition, we investigated the association of RNAs with AGO2 by performing AGO2 immunoprecipitation and total RNA-seq of AGO2-bound RNAs in Mock and RSV-infected A549 cells Overall design: RNA-seq data of A549 cells infected with RSV or mock-treated

为探究呼吸道合胞病毒（Respiratory Syncytial Virus, RSV）感染过程中的RNA表达变化，我们对模拟感染对照（Mock）与RSV感染的A549细胞进行了总RNA测序（total RNA-seq）。此外，我们通过AGO2免疫沉淀（AGO2 immunoprecipitation）实验，并对模拟感染对照和RSV感染的A549细胞中AGO2结合的RNA开展总RNA测序，以此研究RNA与AGO2的结合关联。整体实验设计：取自RSV感染或模拟感染处理的A549细胞的RNA测序数据。