COS6 RNA sequencing

To elucidate the anti-inflammatory mechanism of COS6 on LPS-stimulated RAW264.7 macrophages, RNA-seq technique, the anti-inflammatory effect of COS6 was analyzed. Gene expression levels between COS6 and LPS or LPS and Control were compared to identify differentially expressed genes (DEGs) resulting from COS6 treatment in LPS-stimulated macrophages.

为阐明COS6对脂多糖（Lipopolysaccharide, LPS）诱导的RAW264.7巨噬细胞的抗炎作用机制，本研究采用RNA测序（RNA-seq）技术分析COS6的抗炎效应。通过对比COS6处理组与LPS单独刺激组、LPS单独刺激组与对照组的基因表达水平，鉴定经COS6处理后在LPS激活的巨噬细胞中产生差异表达的基因（differentially expressed genes, DEGs）。