Additional file 15 of Epigenetic reactivation of tumor suppressor genes with CRISPRa technologies as precision therapy for hepatocellular carcinoma
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Additional file 15: Data S4. Related to Fig. 2, Fig. 3, Fig. 4, and Fig. 6. Comparison of the fold change in mRNA expression for the tumor suppressor genes targeted individually or multiplexed by CRISPRa system (SpdCas9-VPR and MS2-MCP-p65-HSF1) versus treatments with the epi-drugs (5-aza and SAHA) in Hep3B and HuH-7 cells.
补充文件15：数据S4。该数据集与图2、图3、图4及图6相关，其内容为对比分别单独靶向或多重靶向抑癌基因的CRISPR激活（CRISPRa）系统（SpdCas9-VPR与MS2-MCP-p65-HSF1），与表观遗传药物（epi-drugs，5-aza及SAHA）处理组在Hep3B与HuH-7细胞中的mRNA表达倍数变化。
提供机构：
Yeoh, George C. T.; Cursons, Joseph; Foroutan, Momeneh; Lyu, Ruqian; Woodward, Eleanor A.; Sgro, Agustin; Blancafort, Pilar; Waryah, Charlene; Leedman, Peter J.
创建时间：
2023-04-30
