Dataset from Step-up Yellow Zone Inhaled Corticosteroids to Prevent Exacerbations

The objective of this study is to determine whether, in children receiving low-dose inhaled corticosteroids (ICS), quintupling the dose of inhaled corticosteroids at the onset of symptoms previously associated with upper respiratory illnesses and subsequent asthma exacerbations reduces the rate of severe asthma exacerbations treated with oral corticosteroids.

本研究旨在明确：对于接受低剂量吸入性糖皮质激素（inhaled corticosteroids，ICS）的儿童，在出现既往与上呼吸道感染及后续哮喘急性加重相关的症状发作时，将吸入性糖皮质激素剂量增至五倍，是否可降低需经口服糖皮质激素治疗的重度哮喘急性加重发生率。