Transcriptome of human pancreatic ductal adenocarcinoma cell line with IGF2BP2 knockdown and control group. Homo sapiens

IGF2BP2 is an mRNA binding protein that can affect the cellular biology function through regulating mRNA turnover. In order to know the downstream gene and biological process affected by IGF2BP2 in PDAC, IGF2BP2 expression was knocked down in PDAC cell line.

IGF2BP2是一种mRNA结合蛋白，可通过调控mRNA周转过程影响细胞生物学功能。为明确IGF2BP2在胰腺导管腺癌（pancreatic ductal adenocarcinoma，PDAC）中调控的下游基因及生物学过程，研究人员在PDAC细胞系中敲低了IGF2BP2的表达。