Intermediate structure of antithrombin bound to the natural pentasaccharide
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Intermediate structure of antithrombin bound to the natural pentasaccharide Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, ... Authors: Huntington, J.A, Belzar, K.J. Deposit date: 2008-10-13 Release date: 2008-10-21 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (3 Å) Cite: The critical role of hinge-region expulsion in the induced-fit heparin binding mechanism of antithrombin. J. Mol. Biol., 386, 2009
与天然五糖（pentasaccharide）结合的抗凝血酶（antithrombin）中间结构
描述：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1-4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、2-脱氧-6-O-磺基-2-(磺氨基)-α-D-吡喃葡萄糖-(1-4)-β-D-吡喃葡萄糖醛酸-(1-4)-2-脱氧-3,6-二-O-磺基-2-(磺氨基)-α-D-吡喃葡萄糖-(1-4)-2-O-磺基-α-L-艾杜吡喃糖醛酸-(1-4)-2-脱氧-6-O-磺基-2-(磺氨基)-α-D-吡喃葡萄糖苷甲酯……
作者：亨廷顿（Huntington, J.A.）、贝尔扎（Belzar, K.J.）
存入日期：2008-10-13
发布日期：2008-10-21
最后修改时间：2024-11-20
实验方法：X射线衍射（3 Å）
引用文献：《抗凝血酶诱导契合肝素结合机制中铰链区挤出的关键作用》，《分子生物学杂志》，第386卷，2009年
创建时间：
2008-10-13
