Wall shear stress at the initiation site of cerebral aneurysms: Vascular models

<strong>License</strong> This data is licensed under a CC-BY-NC license (http://creativecommons.org/licenses/by-nc/3.0/) In addition to the CC-BY-NC license terms, this data is intended for exclusive use by bona fide researchers, according to the MRC Policy on Sharing of Research Data from Population and Patient Studies definition by the Medical Research Council of the United Kingdom (http://www.mrc.ac.uk/research/research-policy-ethics/data-sharing/population-patient-studies/). Any other use is expressly forbidden. If in doubt whether you are allowed to use the data, please contact Prof Alejandro F Frangi ([e-mail]). <strong>Description</strong> Surface mesh representations of part of the cerebral vasculature. Data was created as part of the following study:Geers AJ, Morales HG, Larrabide I, Butakoff C, Bijlenga P, Frangi AF. Wall shear stress at the aneurysm initiation site. Biomechanics and Modeling in Mechanobiology, 16(1):97-115, 2017. Twenty patients, ten cases and ten controls, were drawn from a large multicenter database created within the @neurIST*. The cases were all the patients in the database with an aneurysm on the A1 segment of the anterior cerebral artery (ACA-A1). They were selected because of their remarkable consistency in location: all aneurysms were just distal to the internal carotid artery (ICA) bifurcation with nine cases directed posteriorly and one case directed anteriorly (case 10). Moreover, the location was neither a bifurcation apex nor the outer wall of a vascular bend, which -- attributed to being high WSS regions -- are the most common aneurysm locations. The controls were patients with an aneurysm at the middle cerebral artery (MCA) bifurcation, hence predisposed to having aneurysms, that did not form an aneurysm at the same location as the cases. They were selected to match cases by patient age (within 2 years) and aneurysm hemisphere (left or right). No other information was considered during the selection process. *@neurIST was a project funded by the European Commission (FP6-IST-027703), which ran from Jan 2006 till Mar 2010. Find more information on www.aneurist.org <strong>Files</strong> case01_aneurysm.vtp etc. are the 10 cases with aneurysm. case01.vtp etc. are the 10 cases with the aneurysm virtually removed. control01.vtp etc. are the 10 controls. <strong>Contact</strong>: [e-mail] (Arjan Geers) [e-mail] (Alejandro Frangi)

<strong>许可证</strong> 本数据集采用CC-BY-NC许可协议（http://creativecommons.org/licenses/by-nc/3.0/）。除CC-BY-NC许可条款外，根据英国医学研究理事会（Medical Research Council, MRC）《人口与患者研究数据共享政策》的定义，本数据集仅限符合资质的科研人员专属使用，其他任何使用方式均被明确禁止。若您不确定是否符合使用条件，请联系Alejandro F Frangi教授（邮箱：[e-mail]）。

<strong>数据集描述</strong> 本数据集包含部分脑血管系统的表面网格模型。数据源自以下研究：Geers AJ, Morales HG, Larrabide I, Butakoff C, Bijlenga P, Frangi AF. 动脉瘤起始部位的壁面切应力. 《生物力学与生物力学建模》（Biomechanics and Modeling in Mechanobiology）, 16(1):97-115, 2017.
本数据集的20名受试者取自@neurIST*项目构建的大型多中心数据库，其中包括10例病例与10例对照。病例组均为数据库中大脑前动脉A1段（ACA-A1）存在动脉瘤的患者，筛选依据为病灶位置具有高度一致性：所有动脉瘤均位于颈内动脉（Internal Carotid Artery, ICA）分叉远端，其中9例动脉瘤朝向后方，1例朝向前方（病例10）。此外，该病灶位置既非血管分叉顶点，也非血管弯曲段的外壁——这类区域通常被认为是壁面切应力（Wall Shear Stress, WSS）较高的区域，也是动脉瘤最常见的好发部位。
对照组则为大脑中动脉（Middle Cerebral Artery, MCA）分叉处存在动脉瘤易感倾向，但未在与病例组相同的位置形成动脉瘤的患者。对照组的筛选标准为与病例组在患者年龄（误差不超过2岁）以及动脉瘤所在半球（左侧或右侧）上相匹配，筛选过程未考虑其他信息。
*@neurIST是由欧盟委员会资助（项目编号FP6-IST-027703）的项目，实施周期为2006年1月至2010年3月，更多信息可访问官网www.aneurist.org。

<strong>文件说明</strong> case01_aneurysm.vtp 等文件为10例动脉瘤病例的网格模型；case01.vtp 等文件为10例已虚拟移除动脉瘤的病例网格模型；control01.vtp 等文件为10例对照组的网格模型。

<strong>联系方式</strong> Arjan Geers（邮箱：[e-mail]）；Alejandro Frangi（邮箱：[e-mail]）