Data_Sheet_7_Trends in the global burden of vision loss among the older adults from 1990 to 2019.DOCX

PurposeTo quantify the global impact of vision impairment in individuals aged 65 years and older between 1990 and 2019, segmented by disease, age, and sociodemographic index (SDI).
MethodsUsing the Global Burden of Diseases 2019 (GBD 2019) dataset, a retrospective demographic evaluation was undertaken to ascertain the magnitude of vision loss over this period. Metrics evaluated included case numbers, prevalence rates per 100,000 individuals, and shifts in prevalence rates via average annual percentage changes (AAPCs) and years lived with disability (YLDs).
ResultsFrom 1990 to 2019, vision impairment rates for individuals aged 65 years and older increased from 40,027.0 (95% UI: 32,232.9-49,945.1) to 40,965.8 (95% UI: 32,911-51,358.3, AAPC: 0.11). YLDs associated with vision loss saw a significant decrease, moving from 1713.5 (95% UI: 1216.2–2339.7) to 1579.1 (95% UI: 1108.3–2168.9, AAPC: −0.12). Gender-based evaluation showed males had lower global prevalence and YLD rates compared to females. Cataracts and near vision impairment were the major factors, raising prevalence by 6.95 and 2.11%, respectively. Cataract prevalence in high-middle SDI regions and near vision deficits in high SDI regions significantly influenced YLDs variation between 1990 and 2019.
ConclusionOver the past three decades, there has been a significant decrease in the vision impairment burden in individuals aged 65 and older worldwide. However, disparities continue, based on disease type, regional SDI, and age brackets. Enhancing eye care services, both in scope and quality, is crucial for reducing the global vision impairment burden among the older adults.

研究目的：量化1990年至2019年间65岁及以上人群视力损害的全球影响，并按疾病类型、年龄分组及社会人口学指数（sociodemographic index, SDI）进行分层分析。
研究方法：采用2019年全球疾病负担（Global Burden of Diseases 2019, GBD 2019）数据集，开展回顾性人口学评估，以明确该时期内视力损失的疾病负担规模。本次评估的指标包括病例数、每10万人口患病率，以及通过年均变化率（average annual percentage changes, AAPC）和因伤残损失的健康寿命年（years lived with disability, YLDs）分析的患病率动态变化。
研究结果：1990年至2019年，65岁及以上人群的视力损害患病率从40027.0（95%不确定区间（95% UI）：32232.9~49945.1）升至40965.8（95%不确定区间（95% UI）：32911~51358.3，AAPC：0.11）。与视力损失相关的因伤残损失的健康寿命年（YLDs）则出现显著下降，从1713.5（95%不确定区间（95% UI）：1216.2~2339.7）降至1579.1（95%不确定区间（95% UI）：1108.3~2168.9，AAPC：-0.12）。性别分层分析显示，全球范围内男性的患病率及YLDs水平均低于女性。白内障与近视力损害为主要致病因素，分别使患病率提升6.95%和2.11%。高-中社会人口学指数区域的白内障患病率，以及高社会人口学指数区域的近视力缺陷，对1990年至2019年间YLDs的变化产生了显著影响。
研究结论：过去三十年间，全球65岁及以上人群的视力损害负担已显著降低，但不同疾病类型、区域社会人口学指数水平及年龄分组之间仍存在健康差异。扩大并优化眼保健服务的覆盖范围与服务质量，对降低全球老年人群的视力损害负担至关重要。