Penicillium fuscoglaucum Pf_T2 Genome Assembly and Annotation

During routine culturing on selective media in the lab, we obtained an isolate of P. fuscoglaucum Pf_T2 and sequenced its genome. The Pf_T2 genome is far superior to available genomic resources for the species. Our assembly exhibits a length of 35.1 Mb, a BUSCO score of 97.9% complete, and consists of 5 scaffolds/contigs representing the four expected chromosomes. It was determined that the Pf_T2 genome was colinear with a type specimen P. fuscoglaucum, and contained a lineage specific, intact cylcopaizonic acid (CPA) gene cluster.

本研究于实验室选择性培养基上开展常规培养时，分离得到一株暗蓝青霉（P. fuscoglaucum）Pf_T2，并对其基因组进行了测序。该Pf_T2菌株的基因组质量远优于该物种目前已有的基因组资源。本次组装的基因组全长为35.1 Mb，完整BUSCO评分达97.9%，由5个支架/重叠群（scaffolds/contigs）构成，对应该物种预期的4条染色体。经分析确认，Pf_T2的基因组与暗蓝青霉（P. fuscoglaucum）模式菌株具有共线性，且包含一个谱系特异性的完整环帕伊佐酸（cylcopaizonic acid, CPA）基因簇。