Data Sheet 1_Case report: A pregnant woman with recurrent craniopharyngioma: surgical decision-making and doctor-patient bond.docx

Craniopharyngioma is a rare, benign tumor that originates from the pituitary stalk and extends along the pituitary-hypothalamic axis. It can have serious effects due to its location, affecting hormone regulation, vision, and other neurological functions. It is particularly rare and challenging to manage it during pregnancy due to the potential impacts on both maternal and fetal health, requiring careful, individualized treatment. We reported a 26-year-old pregnant woman at 27 weeks with recurrent craniopharyngioma who presented with worsening consciousness and hydrocephalus. Despite recommendations to terminate the pregnancy for tumor resection, she chose to continue. We performed an endoscopic endonasal tumor resection with pituitary transposition to preserve pituitary function, and at 32 weeks, she delivered a healthy baby via cesarean section. We provided a detailed account of the perioperative complications and their management, addressing endocrine, temperature, and fluid regulation challenges. Throughout the process, the medical team maintained open communication with the patient and her family, respecting their desire to continue the pregnancy and exemplifying patient-centered, compassionate care.

颅咽管瘤（Craniopharyngioma）是一种起源于垂体柄、沿垂体-下丘脑轴延伸的罕见良性肿瘤。因其生长位置特殊，可引发严重不良影响，累及激素调节、视力及其他神经功能。妊娠期颅咽管瘤的诊疗尤为罕见且极具挑战，因其可能对母体与胎儿健康均造成潜在危害，因此需要采取谨慎且个体化的治疗策略。本研究报告一例孕27周的26岁孕妇，其复发性颅咽管瘤患者出现意识进行性恶化伴脑积水。尽管临床建议终止妊娠以实施肿瘤切除术，但患者选择继续妊娠。我们为其实施了经鼻内镜肿瘤切除术联合垂体移位术以保留垂体功能，患者于孕32周经剖宫产诞下一名健康婴儿。我们详细记录了围手术期的并发症及其处置方案，针对性解决了内分泌、体温及体液调节等核心难题。整个诊疗过程中，医疗团队与患者及其家属保持充分沟通，尊重其继续妊娠的意愿，充分践行了以患者为中心的人文关怀医疗理念。